Premium natural active ingredients manufactured in GMP-certified facilities to meet global standard specifications.
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) is a leading China manufacturer and exporter of herbal extracts and their derivatives for more than 20 years. We seamlessly combine cutting-edge R&D with advanced industrial manufacturing and global sales channels.
Our comprehensive portfolio focuses on Herbal Extracts, Sweeteners, Nootropics, Vegetable & Fruit Juice Powder, Essential Oils, and Bee Products. Over years of dedicated service, TRB has developed deep expertise in optimizing botanical active compounds such as Icariin in Epimedium Sagittatum, earning us the 2026 "Global Biotechnology and Life Sciences Award" - "Best Global Herbal Extract Provider 2026".
Years Extraction Experience
Exporting Countries
GMP Manufacturing Plants
Traceable Bio-Active Assays
A comprehensive examination of active phytocompounds, standardization markers, and physiological profiles for industrial applications.
Epimedium Sagittatum, recognized in ethnopharmacology for centuries, derives its clinical effectiveness from a family of prenylated flavonol glycosides. Chief among these is Icariin (C33H40O15), which acts as the primary marker compound for standardization. Icariin is biologically active and acts as a selective inhibitor of phosphodiesterase type 5 (PDE5), making it a valuable ingredient in energy and sexual health formulations.
In addition to Icariin, high-quality Epimedium Sagittatum extract contains secondary active metabolites, including Icariside II, Epimedin A, Epimedin B, and Epimedin C. These work together to optimize bioavailability and modulate cellular pathways involved in nitric oxide (NO) production, bone mineralization, and neurological protection.
At TRB, our raw plant selection begins in the high-altitude forests of China, where species density ensures high natural icariin levels. Our processing utilizes High-Performance Liquid Chromatography (HPLC) coupled with Diode Array Detection (HPLC-DAD) to verify exact assay percentages, ranging from 10% to 98% pure Icariin.
This strict level of testing ensures that downstream manufacturers receive powder with minimal batch-to-batch variation, low heavy metals, and no adulterants. This consistency is essential for brands looking to maintain consistent product efficacy.
Addressing the critical engineering, solubility, and regulatory challenges of plant extraction.
We modify bulk density and flowability metrics to meet specific packaging needs. Whether producing hard capsules, pressed tablets, or pre-workout powder mixes, our material flows smoothly through high-speed encapsulation machinery without clogging.
Standard Epimedium powder can have low solubility in liquids. We offer specialized water-soluble grades designed for functional beverages and liquid supplements, producing a clear solution without sedimentation.
We test for synthetic PDE5 inhibitors, heavy metals, Polycyclic Aromatic Hydrocarbons (PAHs), and organic solvent residues. Our products comply with USP, EP, and FDA specifications for purity.
How international supplement brands formulate with Epimedium Sagittatum across major global markets.
In North America, Epimedium is highly sought after for natural sports nutrition and vitality formulations. It is commonly combined with Tongkat Ali (Eurycoma Longifolia), Tribulus Terrestris, and L-Arginine to create targeted wellness products.
In Europe, compliance with EFSA and local regulations requires detailed trace element profiles and guaranteed non-irradiated botanical materials. Our advanced physical processing methods ensure our extracts meet these strict EU import regulations.
Modern neuroscience research shows that Icariin supports neural plasticity and helps mitigate oxidative stress in brain tissues. As a result, B2B buyers are increasingly incorporating low-dose Epimedium extracts into daily cognitive and healthy aging supplements.
From sustainably harvested wild crops to high-purity active crystalline powder.
Raw Epimedium Sagittatum leaves are collected and authenticated via thin-layer chromatography (TLC) to verify the botanical species.
The leaves undergo extraction using food-grade ethanol and water solvents at controlled temperatures, preserving the sensitive glycoside structures of Icariin.
The liquid extract is filtered and concentrated under low pressure. It then passes through adsorption columns to achieve the target Icariin concentration (e.g., 10%, 20%, or 50%).
Drying occurs in a cleanroom environment, followed by sieving, metal detection, and airtight packaging in fiber drums with double food-grade inner bags.
TRB operates three modern manufacturing plants dedicated to botanical extracts, bee products, and animal-derived active compounds. To support global distribution, our facilities maintain a comprehensive list of international food safety and quality certifications:
Every shipment is accompanied by a batch-specific Certificate of Analysis (COA), heavy metal profiles, pesticide residue assays, and microbiological reports.
Quick answers to common questions about sourcing, formulating, and importing bulk Epimedium powder.
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