Founded on rigorous science and global service excellence, Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) has served as China’s leading manufacturer and exporter of botanical extracts and active functional ingredients for over 20 years. We merge cutting-edge biological research, industrial-scale clean manufacturing, and strict international standard distribution.
Our commitment to excellence has earned us the prestigious 2026 Global Biotechnology and Life Sciences Award, recognizing TRB as the ''Best Global Herbal Extract Provider 2026''. From high-purity natural sweeteners to advanced nootropics and standardized herbal derivatives, we guarantee traceable, safe, and effective ingredient supplies to global enterprises.
Export Countries
State-of-the-Art Factories
HACCP & GMP Compliant
TRB operates three independent, fully automated manufacturing facilities specialized for distinct extraction types: a dedicated Herbal Extract Plant, a specialized Bee Products Facility, and an advanced Animal Extract Plant. Our quality management systems are certified across critical international compliance baselines, ensuring seamless market entry:
Our focus in recent years highlights breakthrough developments in Nootropics and Longevity Sciences. We synthesize and standardize high-demand therapeutic derivatives like Brain Health Herbs, Anti-Aging natural compounds, and overall Longevity factors, generating outstanding global feedback and scientific validation.
Understanding the molecular complexity, active biomarkers, and technical specifications of premium Semen Cassiae extracts.
Cassia Seed Extract (derived from the seeds of Cassia obtusifolia L. or Cassia tora L.) is a major botanical raw material with deep roots in traditional applications and modern clinical pharmacognosy. Characterized by its complex organic constitution, the therapeutic efficiency of Cassia Seed Extract lies in its rich profile of active secondary metabolites—most notably anthraquinones, glycosides, flavonoids, and polysaccharides.
As a leading global supplier, TRB standardizes Cassia Seed Extract to ensure consistent levels of key biomarker components, primarily Chrysophanol, Emodin, Physcion, Rhein, and Obtusifolin. These compounds act synergistically to deliver pharmacological benefits such as ophthalmic cell protection (improving visual acuity), lipid metabolism regulation, anti-inflammatory defense, and mild gastrointestinal motility support.
| Specification Parameter | Standard Limit / Range | Testing Methodology (USP/EP) |
|---|---|---|
| Active Marker (Total Anthraquinones) | 1.0% - 5.0% Min (Customization Available) | HPLC-DAD / UV-Vis |
| Extraction Ratio | 5:1, 10:1, 20:1 TLC certified | TLC (Thin Layer Chromatography) |
| Appearance | Fine Brownish-Yellow Powder | Visual Inspection |
| Mesh Size | 95% passing through 80 Mesh | Analytical Sieve Analysis |
| Loss on Drying | ≤ 5.0% Max | Gravimetric (105°C, 3 Hours) |
| Heavy Metals (Pb, As, Cd, Hg) | Lead ≤ 1.0 ppm, Arsenic ≤ 0.5 ppm, Cadmium ≤ 0.2 ppm | ICP-MS (Inductively Coupled Plasma Mass Spectrometry) |
| Microbiological Count | Total Plate Count < 1,000 cfu/g, Yeast & Mold < 100 cfu/g | EP / USP Microbiological Test Limits |
| Solvent Residues | Ethanol Only (Class 3 Solvent) ≤ 5000 ppm | GC-HS (Gas Chromatography-Headspace) |
*Note: Standardized options without carriers (maltodextrin-free) and fully water-soluble formulas optimized for functional beverages are available upon request from our R&D department.
How TRB pioneers biological engineering to optimize active yields and eliminate processing impurities.
By deploying targeted pectinase and cellulase enzyme pre-treatment systems, we break down the rigid seed coat of Cassia seeds at a molecular level. This increases the extraction yield of free anthraquinones by up to 28% without degrading their delicate chemical structure.
Traditional Cassia extracts face issues with turbidity and sediment when dissolved. TRB utilizes advanced ceramic cross-flow membrane filtration to isolate macromolecular lipids, starches, and tannins. The resulting powder achieves near-perfect clarity in aqueous solutions.
Recognizing the strict regulatory landscapes in the EU and USA regarding free emodin levels (which can cause unwanted laxative effects in high doses), TRB utilizes dynamic molecular sieve chromatography to selectively reduce target anthraquinones to customized safe thresholds while retaining maximum therapeutic antioxidant profiles.
Tailored formulations and particle parameters matching the specific production requirements of your industry.
For cognitive and brain health supplements, Cassia Seed Extract acts as an indirect protective agent for ophthalmic nerves. We supply high-density powders optimized for hard-shell encapsulation and direct compression tableting, ensuring optimal flowability and minimal tooling wear.
Our instant-dissolve, water-soluble Cassia Seed Extract series is de-bittered and treated to prevent precipitation. This matches the formulation needs of RTD herbal teas, detox beverages, and powder drink mixes requiring clean sensory profiles and stable shelf lives.
Leveraging the natural gut-regulatory and antimicrobial characteristics of Cassia anthraquinones, our feed-grade bulk extract serves as an effective natural alternative to growth promoters, boosting immune response and digestive wellness in livestock and poultry.
In an era of global volatility, securing a dependable active ingredient supply chain is critical. Nanjing Tong Rui Bio-Tech (TRB) mitigates supply chain risks through intensive vertical integration:
Streamlining the path to market with flawless legal documentation, custom clearances, and physical localized stock networks.
Full support for FDA dietary supplement regulatory filings. We provide complete structural safety dossiers, NDIs (New Dietary Ingredients), and heavy metal compliance reports matching California Proposition 65 regulations.
Navigating the EFSA standards. We provide certified testing demonstrating pesticide profiles within limits established by the European Pharmacopoeia (EP 2.8.13) and monitor polycyclic aromatic hydrocarbon (PAH) limits carefully.
Through our established shipping partners and localized warehousing structures, we facilitate seamless customs clearance. We offer DDP (Delivered Duty Paid) shipping to major ports and logistics hubs across Europe and North America.
Technical answers for procurement, quality assurance, and product development managers.
With products actively exported to over 60 countries, TRB has established robust supply relationships across Europe, Asia Pacific, and the Americas. By standardizing every phase of our extraction loop, we help client brands launch high-potency formulations with complete regulatory compliance.
We are committed to the research, development, and scaling of pure, natural plant extracts, delivering wellness ingredients backed by rigorous science.
Request samples, custom specifications, or a wholesale quotation today.
+86-25-52863298
+86-13770771528
Fax: 86-25-52867040
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
