Explore our high-purity natural extracts optimized for pharmaceutical, nutraceutical, and cosmetic formulations.
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) has stood at the forefront of natural ingredient extraction, serving as a leading China manufacturer and exporter of standard herbal extracts and their derivatives for more than 20 years.
As a technology-based enterprise, we seamlessly integrate advanced research & development, state-of-the-art production facilities, and customer-focused global sales channels. Our comprehensive product portfolio spans high-purity Herbal Extracts, Sweeteners, Nootropics, Fruit & Vegetable Juice powders, Essential Oils, and Bee Products.
Operating with the understanding that our botanical extracts serve sensitive pharmaceutical and food-grade markets, TRB manages three modern production bases: a dedicated herbal extract factory, a specialized bee product facility, and a modern animal extraction plant.
Each facility conforms to stringent international standards, holding a robust array of compliance certifications including: GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER.
In recent years, our R&D group has achieved significant breakthroughs in Nootropics, Anti-Aging, and Longevity formulations, receiving exceptional feedback from clinical research organizations, cosmetic brands, and pharmaceutical buyers worldwide.
Artemisinin (extracted from Artemisia annua L., commonly known as sweet wormwood) is a sesquiterpene lactone containing an unusual peroxide bridge. This endoperoxide 1,2,4-trioxane structure is chemically unique and responsible for the compound's rapid clearance of Plasmodium falciparum parasites within the human bloodstream. As the foundation of Artemisinin-based Combination Therapies (ACTs) recommended by the World Health Organization (WHO), high-purity industrial Artemisinin remains one of the world's most critical therapeutic compounds.
From an industrial perspective, sourcing premium-grade raw Artemisinin is crucial. Manufacturers and contract research organizations (CROs) require high-purity active pharmaceutical ingredients (APIs) to synthesize derivatives such as Artemether, Artesunate, and Dihydroartemisinin. Purity profiles, moisture content, and heavy metal concentrations must be tightly managed to meet international pharmacopoeia standards (USP, EP, IP).
| Specification Parameter | Standard Specification (USP/EP Grade) | TRB Quality Target |
|---|---|---|
| Appearance | White crystalline powder or needles | Conforms (Pure white crystal) |
| Assay (HPLC-UV / HPLC-ELSD) | 98.0% ~ 102.0% | ≥ 99.5% |
| Specific Optical Rotation | +75° to +78° | +76.5° |
| Loss on Drying | ≤ 0.5% | 0.28% |
| Heavy Metals (as Pb) | ≤ 10 ppm | ≤ 2 ppm |
| Residual Solvents | Conforms to ICH Q3C limits | Ethanol/Hexane free |
The global availability of Artemisinin is closely tied to agricultural and technological developments in China. For decades, the mountainous terrain and temperate climates of provinces like Sichuan, Guangxi, and Chongqing have provided optimal cultivation environments for *Artemisia annua* plants, which require specific day-length variations and soil chemistry to maximize biosynthesized artemisinic acid.
As a leading China manufacturer, TRB leverages this geographical advantage by utilizing vertically integrated supply contracts. By partnering with local farming collectives, we control agricultural inputs, minimize pesticide exposure, and track seasonal growth patterns to harvest at the exact physiological peak of active compound concentration. This integrated approach ensures consistent pricing, high yields, and uninterrupted supply chains for global buyers, mitigating the fluctuations that often affect agricultural extraction industries.
Utilizing low-temperature supercritical carbon dioxide extraction processes allows for the separation of thermal-sensitive peroxide structures without risking structural degradation or chemical rearrangement.
Our proprietary multi-stage recrystallization process using safe, non-toxic solvents ensures the final crystalline structure maintains a stable form with high chemical purity.
Every industrial run undergoes strict HPLC monitoring, verifying that related impurities (such as artemisinin B and other terpene derivatives) remain well within international regulatory limits.
In the pharmaceutical ingredient industry, trust is built on comprehensive documentation. Regulatory authorities globally require detailed evidence of purity and process control. TRB addresses these requirements by maintaining complete traceability: from the initial agricultural soil assessment, through raw herb storage, up to the final validated packaging steps.
We provide global partners with a full documentation package, including Drug Master Files (DMF) support, certificates of analysis (CoA) for every batch, allergen statements, BSE/TSE-free certifications, and heavy metal testing profiles. By aligning our production methodologies with both United States Pharmacopeia (USP) and European Pharmacopoeia (EP) guidelines, TRB ensures regulatory compliance for international pharmaceutical registrations.
Furthermore, our dedicated analytical laboratories are equipped with modern instruments (HPLC, GC-MS, ICP-OES for heavy metal detection, and microbiological testing setups). This in-house analytical capability allows us to issue reliable analytical documentation, reducing testing lead times and accelerating custom-clearance procedures for our clients.
Industrial applications of Artemisinin and its derivatives vary across global regions, requiring flexible supply arrangements:
To support these varied applications, TRB offers customizable packaging (from 1kg aluminum foil bags to 25kg fiber drums), temperature-controlled shipping configurations, and rapid containerized dispatch from major logistics hubs like Shanghai and Ningbo ports.
Expert insights regarding procurement, technical specifications, and distribution of wholesale Artemisinin.
Further expand your product portfolio with our certified, high-yield plant and fruit concentrates.
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
86-25-52863298
86-13770771528
86-25-52867040
