China Luteolin Manufacturer & Supplier

High-Purity Natural Luteolin Extracts for Global Pharmaceutical, Nutraceutical, and Cosmetic Industries. Backed by 20+ Years of Phytochemical Expertise.

Global Luteolin Market: Commercial & Industrial Landscape

Luteolin (3',4',5,7-tetrahydroxyflavone) is a naturally occurring flavone found in a wide variety of plants, including fruits, vegetables, and medicinal herbs. In recent years, the global demand for Luteolin has surged exponentially, driven by its potent anti-inflammatory, antioxidant, neuroprotective, and anti-tumor properties. As global consumers increasingly shift toward preventative health and longevity supplements, Luteolin has emerged as a cornerstone ingredient in advanced nutraceutical formulations.

From an industrial perspective, Luteolin is primarily sourced from raw materials such as Sophora japonica extract, peanut shells, and various herbal plants. The commercialization of Luteolin requires highly sophisticated extraction and purification technologies to achieve the high purity levels (typically 98% HPLC) demanded by pharmaceutical and high-end dietary supplement brands. As a result, the supply chain is highly concentrated among specialized manufacturers capable of balancing yield, purity, and cost-efficiency.

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Pharmaceutical Grade

Utilized as an active pharmaceutical ingredient (API) in research and formulation targeting chronic inflammatory diseases, metabolic syndromes, and neurodegenerative disorders.

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Nutraceutical & Nootropic

Incorporated into brain health supplements, longevity formulas, and cellular defense products to inhibit microglial activation and support cognitive function.

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Cosmeceutical Applications

Leveraged in premium skincare products for its ability to mitigate UV-induced oxidative stress, reduce skin inflammation, and inhibit melanogenesis.

Nanjing Tong Rui Bio-Tech (TRB): Your Trusted Phytochemical Partner

Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) is a leading China-based manufacturer and exporter of premium herbal extracts and their derivatives, boasting over 20 years of industry experience. Established as a technology-driven enterprise, TRB seamlessly integrates scientific research and development, state-of-the-art production, and global sales distribution.

Our comprehensive product portfolio spans high-quality Herbal extracts, Natural Sweeteners, Nootropics, Vegetable & Fruit Juice powders, Essential oils, and Bee Products. Over the decades, TRB's unwavering commitment to quality and service has earned us prestigious recognition, including the 2026 Global Biotechnology and Life Sciences Award as the "Best Global Herbal Extract Provider 2026".

Multi-Factory Infrastructure & Global Certifications

To meet the diverse demands of our international clientele, TRB operates three specialized manufacturing facilities: one dedicated to herbal extracts (including high-purity Luteolin), one for bee products, and another for animal-derived extracts. Our facilities are fully certified under international quality and safety standards, ensuring complete regulatory compliance across global markets:

GMP Certified ISO 9001 & 22000 HACCP USDA ORGANIC FDA Registered HALAL KOSHER

In recent years, TRB has strategically focused on the R&D of Nootropics and Longevity compounds. Our Brain Health Herb Extracts, Anti-Aging Herb Extracts, and Longevity Herb Extracts have received exceptional feedback from clients in North America, Europe, and Asia-Pacific, establishing TRB as a premier supplier in the global anti-aging sector.

20+
Years of Extraction Expertise
3
State-of-the-Art Factories
60+
Countries Exported To
98%
Standard Luteolin Purity (HPLC)

Why Source Luteolin from China? The TRB Manufacturing Edge

China is the global powerhouse for plant extraction, controlling over 70% of the global herbal extract supply chain. Sourcing Luteolin from a premier Chinese manufacturer like TRB offers significant strategic advantages for global brands:

1. Raw Material Abundance & Supply Chain Integration

China possesses vast agricultural resources for sourcing Luteolin-rich raw materials, particularly Sophora japonica and peanut shells. TRB maintains long-term contract farming agreements, ensuring a stable, traceable, and pesticide-controlled raw material supply. This vertical integration insulates our clients from raw material price volatility and supply shortages.

2. Advanced Extraction & Purification Technology

TRB utilizes proprietary multi-stage crystallization and chromatography technologies to isolate Luteolin. Unlike standard extraction methods that result in low purity or high solvent residues, our process yields Luteolin with a purity of up to 98% HPLC while keeping residual solvents (such as ethanol) well below USP and EP limits. Our state-of-the-art facilities are equipped with automated production lines that maximize yield and minimize human error.

3. Cost-Efficiency & Economies of Scale

By operating three large-scale manufacturing plants, TRB achieves significant economies of scale. We pass these cost savings directly to our partners, offering highly competitive wholesale pricing without compromising on quality. Furthermore, our location in Nanjing provides excellent logistics infrastructure, enabling rapid shipping via major air and sea ports.

Localized Application Scenarios & Formulation Trends

Luteolin's versatile biological activities make it highly sought after across various regional markets, each focusing on distinct application scenarios:

North America: Cognitive Health & Nootropic Blends

In the United States and Canada, there is a booming demand for nootropics that support focus, memory, and brain longevity. Luteolin is frequently formulated alongside Palmitoylethanolamide (PEA) or Rutin to create synergistic blends that target neuroinflammation and support microglial health. TRB provides micronized Luteolin powder to enhance bioavailability in capsule and tablet formulations.

Europe: Healthy Aging & Senolytic Formulations

European consumers are highly focused on healthy aging and preventive medicine. Luteolin is recognized as a potent senolytic agent—a compound that selectively clears senescent cells. It is commonly combined with Quercetin, Fisetin, and Resveratrol in premium anti-aging supplements designed to promote cellular rejuvenation and cardiovascular health.

Asia-Pacific: Immune Support & Cosmeceuticals

In the APAC region, particularly in Japan, South Korea, and China, Luteolin is widely used in respiratory health supplements due to its traditional use in soothing coughs and reducing lung inflammation. Additionally, the cosmetic industry utilizes high-purity Luteolin in topical formulations for its skin-soothing, anti-inflammatory, and anti-hyperpigmentation properties.

Global Procurement Standards & Quality Assurance

For global procurement managers, ensuring the quality, safety, and consistency of active ingredients is paramount. TRB adheres to rigorous quality assurance protocols to guarantee that every batch of Luteolin meets international standards:

  • Purity Verification: Every batch is tested using High-Performance Liquid Chromatography (HPLC) to verify active Luteolin content.
  • Heavy Metal Control: Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is used to ensure heavy metals (Lead, Arsenic, Cadmium, Mercury) are well below strict FDA and EU limits.
  • Pesticide Residue Screening: Comprehensive GC-MS/LC-MS testing guarantees compliance with European Pharmacopoeia (EP) and USP standards for pesticide residues.
  • Microbiological Testing: Strict controls for Total Plate Count, Yeast & Mold, E. coli, and Salmonella to ensure product safety.
  • Physical Characterization: Custom particle size distribution (mesh size) and bulk density adjustments are available to suit specific manufacturing requirements.

Frequently Asked Questions (FAQ)

Get authoritative answers to common technical and commercial questions about Luteolin sourcing.

What is the primary botanical source of TRB's Luteolin? +
TRB primarily extracts Luteolin from high-quality *Sophora japonica* (Japanese Pagoda Tree) and natural peanut shells (*Arachis hypogaea*). The choice of raw material depends on the client's specific formulation requirements and regional regulatory preferences.
What purity levels of Luteolin do you manufacture? +
We specialize in manufacturing high-purity Luteolin, with our standard specification being ≥98% Luteolin by HPLC. We can also customize lower concentrations (e.g., 90%, 95%) or supply custom blends based on your formulation needs.
How does TRB ensure the heavy metal and pesticide limits comply with EU/US regulations? +
Every batch of our Luteolin undergoes rigorous testing in our in-house laboratory and is validated by third-party ISO/IEC 17025 accredited laboratories (such as SGS or Eurofins). We guarantee compliance with USP, EP, and California Proposition 65 limits.
What is the minimum order quantity (MOQ) for bulk Luteolin? +
Our standard MOQ for commercial batches of Luteolin is 25kg (packaged in fiber drums with double plastic bags inside). However, for trial phases and formulation testing, we can provide smaller sample quantities (e.g., 1kg to 5kg).
Does TRB offer custom micronization or formulation services? +
Yes, we offer custom physical processing, including micronization (reducing particle size to 80 mesh, 100 mesh, or finer) to improve solubility and bioavailability in finished dosage forms like capsules and tablets.
What certifications do your manufacturing facilities hold? +
Our factories hold GMP, ISO 9001, ISO 22000, HACCP, Kosher, Halal, USDA Organic, and FDA registration certificates, ensuring seamless customs clearance and compliance in over 60 countries.
What is the shelf life and storage recommendation for bulk Luteolin? +
Our Luteolin has a shelf life of 24 months from the date of manufacture when stored in its original unopened packaging in a cool, dry place away from direct sunlight, moisture, and heat.

Visit Us

Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012

Call Us

Phone: 86-25-52863298

Mobile: 86-13770771528

Fax Icon Fax: 86-25-52867040

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