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Evodiamine is a naturally occurring bioactive indole alkaloid extracted from the fruit of the *Evodia rutaecarpa* (Wu Zhu Yu), a plant highly revered in traditional medicine. As a specialized China Evodiamine Manufacturers & Factory, Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) has pioneered the extraction, isolation, and purification of this compound to meet strict global pharmaceutical and nutraceutical standards.
From a pharmacological perspective, Evodiamine acts as a potent agonist of the Transient Receptor Potential Vanilloid 1 (TRPV1) channel. This mechanism mimics the thermogenic properties of capsaicin but without the associated mucosal irritation or burning sensation. Consequently, Evodiamine has become a premier ingredient in weight management formulations, metabolic health supplements, and sports nutrition products.
Beyond metabolic regulation, emerging scientific literature highlights Evodiamine's potential in anti-inflammatory pathways, cardiovascular support, and neuroprotective applications. Its multi-faceted biological activity makes it a highly sought-after compound for innovative product developers aiming to capture market share in the premium health and wellness sectors.
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) is a leading China-based manufacturer and exporter of herbal extracts and their derivatives, boasting over 20 years of industrial expertise. We are a technology-driven enterprise that seamlessly integrates advanced research and development, state-of-the-art production, and international market distribution.
Our comprehensive product portfolio includes premium Herbal Extracts, Sweeteners, Nootropics, Vegetable & Fruit Juice Powder, Essential Oils, and Bee Products. Due to our rapid development and unwavering dedication to quality, TRB was honored with the prestigious 2026 "Global Biotechnology and Life Sciences Award" as the ''Best Global Herbal Extract Provider 2026''.
TRB currently operates three specialized manufacturing facilities: a dedicated herbal extract factory, a bee product processing plant, and an animal-derived extract facility. All operations are strictly governed by international quality management systems, holding certifications such as GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER.
Analyzing the macroeconomic and scientific shifts driving the demand for premium Evodiamine across global industries.
With rising global obesity rates, consumers are seeking natural, non-stimulant thermogenic agents. Evodiamine's ability to stimulate TRPV1 and increase heat production makes it a core ingredient in clean-label weight management formulations.
As cognitive health becomes a priority for aging demographics, Evodiamine is being researched for its neuroprotective qualities. Its potential to cross the blood-brain barrier and modulate neuroinflammation positions it as a high-value nootropic additive.
Global buyers require raw materials that comply with strict pesticide residue, heavy metal, and solvent limits. TRB's GMP-certified production ensures that our Evodiamine meets the stringent entry criteria of North American and European markets.
At TRB, we utilize advanced extraction technologies to ensure the highest purity and bio-availability of Evodiamine. Our standard specifications range from 10% to 98% purity by HPLC, allowing us to cater to diverse formulation requirements.
Our focus on Nootropics and Brain Health Herb Extracts has driven us to optimize the particle size (micronization) of Evodiamine, enhancing its dissolution rate and absorption profile in finished dosage forms.
How TRB partners with global enterprises to deliver tailored active ingredients and seamless supply chain integration.
We offer micronization services down to D90 < 10 microns to improve the solubility of hydrophobic compounds like Evodiamine. Additionally, we provide custom blending with synergistic ingredients such as green tea extract or caffeine for targeted metabolic health products.
Leveraging our three state-of-the-art factories, we offer full-service contract manufacturing. From raw material extraction to capsule filling, tableting, and custom packaging under strict GMP conditions, we streamline your path to market.
Navigating the complex regulatory landscape of botanical extracts requires a knowledgeable partner. TRB ensures that all shipments of Evodiamine and other herbal extracts are accompanied by comprehensive documentation, including Certificate of Analysis (COA), MSDS, Allergen Statements, Non-GMO Declarations, and BSE/TSE Free Certificates.
Our logistics team is highly experienced in handling customs clearance in major markets, including the United States, European Union, Japan, and South Korea. We offer flexible shipping terms (FOB, CIF, DDP) and maintain strategic warehousing partnerships to ensure prompt delivery and uninterrupted supply chains for our contract clients.
Furthermore, our customer service team provides 24/7 technical support, assisting formulators with compatibility queries, stability data, and regulatory filing requirements.
As a forward-looking biotechnology firm, TRB is continuously investing in the next generation of extraction and formulation technologies. Our R&D roadmap for Evodiamine and related alkaloids focuses on three primary pillars:
By combining traditional botanical wisdom with cutting-edge pharmaceutical science, TRB is committed to providing the global market with sustainable, high-efficacy active ingredients.
Get authoritative answers to technical, regulatory, and commercial questions regarding Evodiamine sourcing.
We offer various specifications ranging from 10% to 98% purity by HPLC. The 98% purity is our standard pharmaceutical and premium nutraceutical grade, presenting as a high-quality crystalline powder.
Every batch of Evodiamine is tested using ICP-MS for heavy metals (Lead, Arsenic, Cadmium, Mercury) and GC-MS/MS for over 300 types of pesticide residues, ensuring compliance with USP, EP, and FDA regulations.
Our three factories hold comprehensive international certifications, including GMP, ISO 9001, ISO 22000, HACCP, USDA ORGANIC, FDA registration, HALAL, and KOSHER.
Yes, we provide micronization services. We can customize the particle size distribution (e.g., D90 < 80 mesh, 100 mesh, or even sub-micron levels) to optimize the dissolution rate and formulation performance of your product.
When stored in the original sealed container in a cool, dry place away from direct light and moisture, our Evodiamine has a shelf life of 24 months. We package our bulk powders in double-layer food-grade PE bags inside fiber drums.
Explore our broader range of standardized botanical extracts, essential oils, and functional ingredients.
Contact our technical sales team for bulk pricing, specifications, and custom formulation inquiries.
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
86-25-52863298
86-13770771528
86-25-52867040