1. Product Overview

Ajuga Turkestanica Extract 10% Turkesterone (HPLC Verified) is a premium, plant-derived phytoecdysteroid concentrate sourced from the leaves of Ajuga turkestanica, a herb native to Central Asia. This extract is standardized to contain 10% Turkesterone, a bioactive compound validated by High-Performance Liquid Chromatography (HPLC) for purity and potency.

2. What is Turkesterone?

Turkesterone is a phytoecdysteroid, a class of plant-derived compounds structurally similar to insect molting hormones. Unlike synthetic anabolic agents, Turkesterone interacts with mammalian systems to upregulate protein synthesis without binding to androgen receptors, minimizing side effects like gynecomastia or liver toxicity.

3. Why Ajuga Turkestanica Extract?

3.1 Botanical Profile

Ajuga turkestanica thrives in the nutrient-rich soils of Uzbekistan and Tajikistan. Its leaves contain up to 0.1–0.3% Turkesterone, the highest among known plant species.

3.2 Extraction Process

Our extract is produced via ethanol-water supercritical CO2 extraction, preserving thermolabile compounds while eliminating solvents. Post-extraction HPLC analysis ensures precise standardization.

Step-by-Step Production:

1. Sustainable Harvesting: Wildcrafted leaves collected during peak growing season.
2. Drying & Milling: Low-temperature dehydration to retain bioactivity.
3. Extraction: Ethanol/water (70:30) at 40°C for 4 hours.
4. Filtration & Concentration: Rotary evaporation under vacuum.
5. Standardization: Adjusted to 10% Turkesterone via HPLC quantification.

4. Key Benefits & Clinical Applications

5. Quality Assurance: HPLC Testing & Certifications

5.1 HPLC Chromatogram Analysis

Every batch undergoes dual-phase HPLC to verify Turkesterone content. A sample chromatogram is provided below:

Testing Parameters:

• Column: C18 reverse-phase (5μm, 250mm x 4.6mm)
• Mobile Phase: Acetonitrile/water (55:45)
• Detection: UV at 245 nm

5.2 Certifications

6. Technical Specifications

7. Mechanism of Action

Turkesterone exerts effects via:

1. mTOR Pathway Activation: Stimulates ribosomal protein synthesis.
2. Androgen Receptor Modulation: Upregulates AR expression without direct binding.
3. Glucose Utilization: Enhances GLUT4 translocation in muscle cells.

8. Dosage & Synergistic Combinations

Recommended Daily Intake:

• Athletes: 500–1,000 mg/day (50–100 mg Turkesterone)
• General Wellness: 250 mg/day

Synergistic Ingredients:

• Ecdysterone (from Spinach): Amplifies anabolic signaling.
• Ashwagandha KSM-66®: Reduces cortisol-induced catabolism.
• BCAAs: Enhances muscle recovery.

9. Safety & Side Effects

Safety Profile:

• LD50: >5,000 mg/kg (rat oral study)
• No Hormonal Disruption: Does not suppress endogenous testosterone.

Reported Side Effects:

• Mild gastrointestinal discomfort in <2% of users.

Contraindications:

• Pregnancy/lactation (due to lack of data).

10. Applications in Nutraceuticals

Product Format Ideas:

• Capsules (500 mg Turkesterone/serving)
• Powder blends for shakes
• Liquid shots with electrolytes

11. Comparative Analysis

12. Sustainability Practices

• Wildcrafting Partnerships: Collaborate with Uzbek farmers using regenerative agriculture.
• Carbon-Neutral Shipping: Offset emissions via reforestation programs.

13. Ordering Information

• Minimum Order Quantity (MOQ): 1 kg
• Packaging: Foil-lined kraft bags (1 kg, 5 kg, 25 kg)
• Lead Time: 2–3 weeks

15. References

1. Isenmann E, et al. (2021). J Int Soc Sports Nutr.
2. Syrov VN. (2000). Pharm Chem J.

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