Explore our premium grade plant extracts and fruit powders manufactured under strict ISO/GMP parameters.
Cissus Quadrangularis (often referred to as Hadjod or Veldt Grape) is a perennial plant of the Vitaceae family that has served as a cornerstone in traditional Ayurvedic systems for centuries. Modern clinical trials have illuminated the molecular mechanisms driving its therapeutic potential, particularly focusing on bone metabolic pathways, systemic inflammation, and lipid regulation.
From a raw pharmaceutical perspective, the efficacy of Cissus Quadrangularis Extract is primarily dictated by its concentration of ketosteroids. These naturally occurring phytosteroids play a critical role in supporting osteoblastogenesis, enhancing collagen synthesis, and mitigating cellular oxidative stress. For commercial buyers in the wellness space, sourcing extracts standardized to exact percentages (typically 2.5% to 20% HPLC) is vital to ensuring batch-to-batch consistency and high-level biological efficacy.
How leading brands leverage Cissus Quadrangularis to capture premium market segments.
As global athletes demand natural alternatives to synthetic recovery boosters, Cissus Quadrangularis has emerged as a premier ingredient. Its capacity to accelerate soft tissue repair and lower systemic markers of joint stress makes it highly sought after for clean-label pre- and post-workout formulations.
The rising silver economy demands clean, side-effect-free joint support. Formulating with Cissus extract offers dual benefits: restoring cartilage degradation markers and promoting healthy bone mineral density (BMD) via osteoblast differentiation.
Clinical trials show that pairing Cissus Quadrangularis with components like Irvingia Gabonensis supports weight management, controls blood sugar fluctuations, and reduces systemic inflammatory cytokines associated with metabolic syndrome.
Achieving consistent levels of phytosteroids requires sophisticated botanical chemical engineering. Our process is optimized to prevent degradation of temperature-sensitive ketosteroids and preserve key co-factors.
Cultivated in certified, pesticide-free regions to maximize natural phytosteroid expressions.
An optimized extraction ratio utilizing low temperatures to preserve complex biological compounds.
Continuous column chromatography monitors and guarantees target ketosteroid thresholds (HPLC verified).
Preserves compound viability, generating a highly soluble and stable powder form.
| Parameter | Standard Aqueous | Hydro-Ethanolic (TRB) |
|---|---|---|
| Ketosteroid Yield | Low (< 2.5%) | High (Up to 20%) |
| Bioactive Retention | Moderate | Excellent |
| Solubility Index | Poor to Moderate | 98% Water-Dispersible |
| Heavy Metals Limits | Inconsistent | USP/EU Compliant |
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) is China's leading manufacturer and exporter of herbal extracts and derivatives, bringing over 20 years of refinement to the global bioscience supply chain.
As a technology-based enterprise, TRB integrates research and development, cutting-edge production lines, and streamlined international sales systems. Our product portfolio spans premium Herbal extracts, Sweeteners, Nootropics, Vegetable & Fruit Juice powders, Essential oils, and Bee Products.
Driven by rapid development and a legacy of service in the plant extract sector, TRB has been honored with the 2026 "Global Biotechnology and Life Sciences Award" - "Best Global Herbal Extract Provider 2026".
TRB operates three specialized factories: one for herbal extracts, one for bee products, and one focused on animal-derived extracts. All locations adhere to top international food safety standards, maintaining GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER Certificates. In recent years, our R&D center has dedicated research to Nootropics, including Brain Health, Anti-Aging, and Longevity Herb Extracts, earning excellent customer feedback worldwide. Our products are exported to more than 60 countries, establishing a stellar reputation. We remain committed to pure botanical R&D, working for the health of all humanity.
Scientific and commercial answers straight from our R&D and regulatory department.
We utilize High-Performance Liquid Chromatography (HPLC) coupled with UV-Vis detector arrays to assay the absolute percentage of active 3-ketosteroids. This method prevents the overestimation of active constituents often caused by basic gravimetric or spectrophotometric assays, ensuring reliable, standardized batches.
Yes. All extraction batches undergo strict inductively coupled plasma mass spectrometry (ICP-MS) tests to ensure compliance with USP <2232> and EP standards for heavy metals (Lead, Cadmium, Arsenic, Mercury). Furthermore, we scan for over 500 pesticide residues to meet strict international food safety regulations.
Unlike simple dried stem powders that offer low bio-absorption and inconsistent active components, TRB's extract is a highly concentrated, standardized powder. We refine the raw material to remove insoluble cellulose while keeping the beneficial biological matrix intact, enhancing bioavailability and product stability in capsules, tablets, and powders.
Yes. Our extraction facility is fully audited and holds GMP, ISO, HACCP, Halal, Kosher, and Organic certifications. Our materials are completely free of genetically modified organisms (non-GMO) and allergens, ensuring compatibility with clean-label products.
Our standard bulk packaging features 25kg fiber drums lined with double-layered polyethylene bags. Under optimal storage conditions—cool, dry, and dark—our Cissus Quadrangularis extract maintains full potency for up to 36 months.
Premium solutions for your next global product development cycle.
Our technical export division responds to RFQs, sample inquiries, and regulatory audits within 24 business hours.
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
Phone: 86-25-52863298
Mobile: 86-13770771528
Fax: 86-25-52867040
