Explore our high-performance botanical extracts, synthesized under rigorous pharmaceutical and food grade manufacturing standards.
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) has flourished for more than 20 years as a leading Chinese research-oriented manufacturer and international exporter of standardized herbal extracts and advanced biochemical derivatives. By combining cutting-edge industrial technology, state-of-the-art purification techniques, and comprehensive supply-chain control, we service international markets with premium botanicals geared towards therapeutics, functional nutrition, and craft brewing.
Our rapid expansion and dedication to quality in the phytopharmacological industry earned us the prestigious 2026 Global Biotechnology and Life Sciences Award — naming us "Best Global Herbal Extract Provider 2026."
TRB operates three modern manufacturing facilities dedicated to specific extractions: a high-efficiency plant botanical facility, a specialized bee product production line, and a biochemical animal-derived extraction site. All facilities are fully audited and comply with stringent global quality requirements, securing certifications such as GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER.
A comprehensive examination of Humulus lupulus bio-active compounds and our analytical parameters.
Hops (Humulus lupulus L.) represent a complex matrix of secondary metabolites synthesized within the lupulin glands of the female inflorescence. These constituents are segmented into three primary chemical families, each demanding customized extraction, concentration, and stabilization workflows:
Xanthohumol (XN) is a unique, highly valued prenylated flavonoid. Celebrated for its high-potency antioxidant capacity (many times stronger than tocopherol or EGCG) and anti-inflammatory attributes. TRB specializes in standardizing Xanthohumol from 5% up to 98% purity using molecular distillation.
Alpha acids (Humulone, Cohumulone, Adhumulone) and Beta acids (Lupulone, Colupulone) define both the preservative strength and bittering properties of hops. Our production line stabilizes these compounds, ensuring optimal isomerization when deployed in commercial brewing applications.
Recognized as one of the most potent phytoestrogens discovered, 8-Prenylnaringenin (8-PN) offers therapeutic advantages in post-menopausal care products. TRB implements precise extraction and chromatography methods to separate and isolate this compound at highly standardized ratios.
| Active Ingredient | Common Specifications | Assay Method | Primary Industrial Applications |
|---|---|---|---|
| Xanthohumol (XN) | 5%, 10%, 20%, 98% Powder / Granular | HPLC-UV | Dietary supplements, anti-aging cosmetics, metabolic health formulations |
| Total Prenylflavonoids | 10% - 20% Standardized Complex | HPLC | Sleep aid capsules, phytoestrogenic formulas, wellness tonics |
| Alpha Acids (Humulones) | 30% - 50% Liquid / Paste | HPLC / Spectrophotometry | Industrial brewing, organic beer preservation, natural anti-bacterials |
| Beta Acids (Lupulones) | 10% - 20% CO2 Extract | HPLC | Natural preservative systems, agricultural biocides, livestock gut-health |
How TRB implements supercritical fluid extraction (SFE-CO2) to yield premium hop extracts.
Traditional solvent-based extractions (utilizing ethanol or chlorinated solvents) often compromise delicate botanical fractions or leave chemical residues. To counter this, TRB utilizes high-throughput Supercritical CO2 (Carbon Dioxide) Extraction. This state-of-the-art tech operates under low-temperature conditions, isolating volatile components without oxidation or thermal degradation.
Premium hops sourced directly from certified farms are milled at cryogenic temperatures to prevent volatile terpene and lupulin loss.
Liquid carbon dioxide is pressurized beyond its critical point (73.8 bar, 31.1°C), acting as a solvent to strip lupulin oils cleanly.
The raw hop concentrate is separated into distinct fractions (essential oils, alpha/beta acids, and flavonoids) via molecular distillation.
Fractions are standardized with clean excipients and scrutinized under high-performance liquid chromatography before packaging.
Years Industry Experience
GMP Audited Factories
Export Countries & Regions
HPLC & GC-MS Verified Batch Quality
How TRB addresses requirements across diverse manufacturing sectors.
Stabilized CO2 extracts provide consistent alpha-acid profiles, optimizing bittering efficiency, minimizing shipping bulk, and eliminating vegetative sediment in brewing vessels. Offers long shelf-life and reduces storage volume compared to traditional hop pellets.
Our research-driven focus on nootropic applications leverages hops' natural calming properties. Standardized prenylflavonoids are combined with sleep-support formulations, stress-management capsules, and memory-support botanical blends to enhance neural recovery.
Hops beta acids function as potent antimicrobial agents, inhibiting Gram-positive bacteria. This makes them ideal for clean-label food preservation, natural cosmetics shelf-life extension, and animal feed additives seeking antibiotic alternatives.
Combining domestic raw material access with cutting-edge production to yield reliable ingredient options.
The botanical extract market demands stable pricing, year-round raw material availability, and strict traceability. Operating out of Nanjing, China, TRB utilizes modern logistics hubs and domestic hop cultivation fields located along optimal agricultural lines. This strategic setup ensures consistent, secure raw material supplies and insulation against unpredictable global supply chain fluctuations.
Our production facilities utilize automated control loops to monitor pressure, temperature, and CO2 flow rates in real-time. This reduces human error, guarantees batch-to-batch consistency, and lowers operational overhead. We pass these cost efficiencies directly to our international clients, offering highly competitive pricing structures without compromising quality control.
Navigating international food safety and biochemical import frameworks with complete documentation.
As a global supplier, TRB designs every compliance process to simplify your import and registration workflows. From initial documentation through customs clearance, we back our shipments with comprehensive certification files:
We document pesticide residue profiles (USP/EP standards), heavy metal limits (Pb, As, Hg, Cd), and microbial assays for every batch, issuing detailed Certificates of Analysis (COA).
Our factories maintain active GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER registrations, meeting complex regulatory mandates across the EU, North America, and Southeast Asia.
We offer customs-bonded warehouse integrations, specialized anti-moisture packaging, and temperature-controlled shipping to preserve bio-active compounds in transit.
Detailed technical answers for procurement directors, product developers, and quality control managers.
Expand your product formulations with our diverse range of standardized extracts, manufactured in our certified facilities.
Connect with our technical sales division to request technical specifications, custom formulations, and product quotes.
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